عامل النمو المحول بيتا 1

TGFB1
بنى متوفرة
بنك بيانات البروتين	Ortholog search: PDBe RCSB
قائمة رموز معرفات بنك بيانات البروتين
	1KLA, 1KLC, 1KLD, 3KFD, 4KV5
معرفات
أسماء بديلة	TGFB1, CED, DPD1, LAP, TGFB, TGFbeta, transforming growth factor beta 1, IBDIMDE, TGF-beta1
معرفات خارجية	الوراثة المندلية البشرية عبر الإنترنت 190180 MGI: MGI:98725 HomoloGene: 540 GeneCards: 7040
علم الوجود الجيني
وظائف جزيئية	• type II transforming growth factor beta receptor binding; • protein N-terminus binding; • cytokine activity; • enzyme binding; • growth factor activity; • GO:0003823، GO:0051635 antigen binding; • type I transforming growth factor beta receptor binding; • protein homodimerization activity; • protein serine/threonine kinase activator activity; • GO:0001948، GO:0016582 ربط بروتيني; • protein heterodimerization activity; • type III transforming growth factor beta receptor binding; • transforming growth factor beta receptor binding; • identical protein binding;
مكونات خلوية	• سيتوبلازم; • الفراغ خارج الخلية; • نواة; • زغيبة; • cell surface; • blood microparticle; • غشاء خلوي; • حبيبة إفرازية; • محور عصبي; • جسم الخلية العصبية; • تجويف غولجي; • platelet alpha granule lumen; • GO:0005578 نسيج بيني خارج الخلية; • خارج خلوي;
عمليات حيوية	• positive regulation of histone deacetylation; • positive regulation of transcription regulatory region DNA binding; • ureteric bud development; • tolerance induction to self antigen; • positive regulation of protein phosphorylation; • endoderm development; • response to cholesterol; • positive regulation of MAP kinase activity; • regulation of sodium ion transport; • response to progesterone; • negative regulation of cell cycle; • response to organic substance; • تطور الثدي; • T cell homeostasis; • negative regulation of ossification; • negative regulation of hyaluronan biosynthetic process; • protein phosphorylation; • T cell differentiation; • positive regulation of vascular permeability; • animal organ regeneration; • positive regulation of blood vessel endothelial cell migration; • negative regulation of epithelial cell proliferation; • regulation of binding; • inner ear development; • myelination; • negative regulation of macrophage cytokine production; • تكاثر خلوي; • transforming growth factor beta receptor signaling pathway; • face morphogenesis; • negative regulation of cell population proliferation; • positive regulation of receptor clustering; • regulation of apoptotic process; • positive regulation of collagen biosynthetic process; • cellular response to transforming growth factor beta stimulus; • pathway-restricted SMAD protein phosphorylation; • regulation of DNA binding; • regulation of actin cytoskeleton reorganization; • negative regulation of fat cell differentiation; • GO:0051247، GO:0051200 positive regulation of protein metabolic process; • cell-cell junction organization; • negative regulation of myoblast differentiation; • positive regulation of protein kinase B signaling; • common-partner SMAD protein phosphorylation; • positive regulation of branching involved in ureteric bud morphogenesis; • SMAD protein signal transduction; • epidermal growth factor receptor signaling pathway; • macrophage derived foam cell differentiation; • negative regulation of blood vessel endothelial cell migration; • positive regulation of protein dephosphorylation; • extrinsic apoptotic signaling pathway; • negative regulation of extracellular matrix disassembly; • mitotic cell cycle checkpoint signaling; • positive regulation of fibroblast proliferation; • negative regulation of cell differentiation; • regulation of branching involved in mammary gland duct morphogenesis; • positive regulation of exit from mitosis; • negative regulation of transforming growth factor beta receptor signaling pathway; • negative regulation of gene expression; • morphogenesis of a branching structure; • regulation of SMAD protein signal transduction; • positive regulation of peptidyl-serine phosphorylation; • cell activation; • negative regulation of neuroblast proliferation; • GO:0060469، GO:0009371 positive regulation of transcription, DNA-templated; • نمو الخلايا; • negative regulation of T cell proliferation; • response to wounding; • negative regulation of cell growth; • positive regulation of chemotaxis; • protein export from nucleus; • regulation of protein import into nucleus; • positive regulation of peptidyl-tyrosine phosphorylation; • positive regulation of protein import into nucleus; • positive regulation of cardiac muscle cell differentiation; • oligodendrocyte development; • positive regulation of interleukin-17 production; • inflammatory response; • negative regulation of interleukin-17 production; • lymph node development; • T cell activation; • Notch signaling pathway; • GO:0033128 negative regulation of protein phosphorylation; • regulation of blood vessel remodeling; • SMAD protein complex assembly; • regulation of striated muscle tissue development; • response to vitamin D; • chondrocyte differentiation; • regulatory T cell differentiation; • regulation of cartilage development; • branch elongation involved in mammary gland duct branching; • positive regulation of bone mineralization; • positive regulation of epithelial cell proliferation; • حمل أنثوي; • GO:1904579 cellular response to organic cyclic compound; • positive regulation of extracellular matrix assembly; • cellular calcium ion homeostasis; • التئام الجروح; • GO:1901227 negative regulation of transcription by RNA polymerase II; • response to glucose; • positive regulation of epithelial to mesenchymal transition; • cellular response to dexamethasone stimulus; • negative regulation of production of miRNAs involved in gene silencing by miRNA; • GO:0019049، GO:0030683 mitigation of host defenses by virus; • lens fiber cell differentiation; • positive regulation of NF-kappaB transcription factor activity; • extracellular matrix assembly; • ATP biosynthetic process; • hematopoietic progenitor cell differentiation; • regulation of interleukin-23 production; • positive regulation of protein secretion; • frontal suture morphogenesis; • تحول طلائي - لحمي متوسط; • phosphate-containing compound metabolic process; • تنظيم التعبير الجيني; • adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains; • negative regulation of release of sequestered calcium ion into cytosol; • response to radiation; • mononuclear cell proliferation; • GO:0045996 negative regulation of transcription, DNA-templated; • negative regulation of T cell activation; • positive regulation of odontogenesis; • lipopolysaccharide-mediated signaling pathway; • positive regulation of protein localization to nucleus; • response to estradiol; • regulation of cell migration; • response to hypoxia; • hyaluronan catabolic process; • negative regulation of phagocytosis; • GO:1904578 response to organic cyclic compound; • positive regulation of protein-containing complex assembly; • protein kinase B signaling; • negative regulation of cell-cell adhesion; • GO:1905617 negative regulation of gene silencing by miRNA; • positive regulation of regulatory T cell differentiation; • cellular response to growth factor stimulus; • positive regulation of pathway-restricted SMAD protein phosphorylation; • mammary gland branching involved in thelarche; • response to laminar fluid shear stress; • GO:0010260 شيخوخة; • regulation of regulatory T cell differentiation; • platelet degranulation; • negative regulation of DNA replication; • myeloid dendritic cell differentiation; • salivary gland morphogenesis; • receptor catabolic process; • MAPK cascade; • positive regulation of histone acetylation; • regulation of transforming growth factor beta receptor signaling pathway; • positive regulation of phosphatidylinositol 3-kinase activity; • negative regulation of protein localization to plasma membrane; • positive regulation of NAD+ ADP-ribosyltransferase activity; • negative regulation of immune response; • regulation of cell population proliferation; • negative regulation of skeletal muscle tissue development; • positive regulation of peptidyl-threonine phosphorylation; • positive regulation of smooth muscle cell differentiation; • positive regulation of isotype switching to IgA isotypes; • connective tissue replacement involved in inflammatory response wound healing; • ossification involved in bone remodeling; • positive regulation of apoptotic process; • positive regulation of vascular endothelial growth factor production; • positive regulation of superoxide anion generation; • digestive tract development; • هجرة الخلية; • positive regulation of fibroblast migration; • positive regulation of cell division; • germ cell migration; • GO:0003257، GO:0010735، GO:1901228، GO:1900622، GO:1904488 ضبط زيادي للنسخ انطلاقا من محفز بوليميراز الرنا الثاني; • negative regulation of mitotic cell cycle; • positive regulation of SMAD protein signal transduction; • positive regulation of pri-miRNA transcription by RNA polymerase II; • GO:1901313 positive regulation of gene expression; • ضبط زيادي للتكاثر الخلوي; • تجدد الكبد; • regulation of epithelial to mesenchymal transition involved in endocardial cushion formation; • positive regulation of mononuclear cell migration; • cellular response to insulin-like growth factor stimulus; • positive regulation of cell migration; • response to immobilization stress; • cellular response to mechanical stimulus; • cellular response to ionizing radiation; • تكون الأوعية; • neural tube closure; • heart valve morphogenesis; • نماء القلب; • neural tube development; • membrane protein intracellular domain proteolysis; • leukocyte migration; • ventricular cardiac muscle tissue morphogenesis; • positive regulation of ERK1 and ERK2 cascade; • transforming growth factor beta receptor signaling pathway involved in heart development; • embryonic liver development; • BMP signaling pathway; • نشوء الخلية; • GO:0097285 استماتة; • regulation of pri-miRNA transcription by RNA polymerase II; • positive regulation of production of miRNAs involved in gene silencing by miRNA; • regulation of signaling receptor activity;
	المصادر:Amigo / QuickGO
نمط التعبير عن الحمض النووي الريبوزي
	; ;
	المزيد من بيانات التعبير المرجعية
تماثلات متسلسلة
	P01137
	P04202
	NM_000660 XM_011527242، NM_000660
	XM_036152883 NM_011577، XM_036152883
	XP_011525544 NP_000651، XP_011525544
	XP_036008776 NP_035707، XP_036008776
	ويكي بيانات
اعرض/عدّل إنسان	اعرض/عدّل فأر

عامل النمو المحول بيتا 1 (بالانجليزى: TGFB1) هوا چين موجود فى الانسان العاقل بيشفره transforming growth factor beta 1.^[1]^[2]^[3]

الوظيفه

الحته دى من الصفحه دى فاضيه, ساعد ف كتابتها.

الاهميه

الحته دى من الصفحه دى فاضيه, ساعد ف كتابتها.

لينكات برانيه

عامل النمو المحول بيتا 1 معرف حمض نووى ريبوزى ناقل فى معرف تسلسل المرجع (الإنجليزية)
عامل النمو المحول بيتا 1 معرف حمض نووى ريبوزى ناقل فى معرف تسلسل المرجع (الإنجليزية)
عامل النمو المحول بيتا 1 معرف جين انتريه (الإنجليزية)
عامل النمو المحول بيتا 1 معرف انزمبل جين (الإنجليزية)
عامل النمو المحول بيتا 1 معرف نسخة انزمبل (الإنجليزية)
عامل النمو المحول بيتا 1 معرف نسخة انزمبل (الإنجليزية)
عامل النمو المحول بيتا 1 معرف نسخة انزمبل (الإنجليزية)
عامل النمو المحول بيتا 1 معرف نسخة انزمبل (الإنجليزية)
عامل النمو المحول بيتا 1 معرف نسخة انزمبل (الإنجليزية)
عامل النمو المحول بيتا 1 معرف قاعدة البيانات الحره (Freebase) (الإنجليزية)
عامل النمو المحول بيتا 1 رمز جين فى منظمة مشروع الجينوم البشرى (الإنجليزية)
عامل النمو المحول بيتا 1 معرف لجنة تسميات جين هوجو (الإنجليزية)
عامل النمو المحول بيتا 1 معرف وراثه مندليه بشريه (الإنجليزية)
عامل النمو المحول بيتا 1 معرف مايكروسوفت الاكاديمى (الإنجليزية)

مصادر

↑ "What is a gene?: MedlinePlus Genetics". medlineplus.gov (بالإنجليزية). Retrieved 2022-01-25.
↑ "Gene". Genome.gov (بالإنجليزية). Retrieved 2022-01-25.
↑ "Genes: Function, makeup, Human Genome Project, and research". www.medicalnewstoday.com (بالإنجليزية). 14 Mar 2017. Retrieved 2022-01-25.

لم يتم العثور على روابط لمواقع التواصل الاجتماعي.

[1] "What is a gene?: MedlinePlus Genetics". medlineplus.gov (بالإنجليزية). Retrieved 2022-01-25.

[2] "Gene". Genome.gov (بالإنجليزية). Retrieved 2022-01-25.

[3] "Genes: Function, makeup, Human Genome Project, and research". www.medicalnewstoday.com (بالإنجليزية). 14 Mar 2017. Retrieved 2022-01-25.

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